Paper focuses on the issues of “difficult questions” in research, especially those, concerning gender and sexuality. It points out three main levels of “difficulties”: formulating the research questions, asking the questions during research and analysing the answers. Each of the stages of research may become problem–prone, especially when the issue of gender and sexuality is taken into account. However, if those issues are ignored by the researcher, the difficulties do not disappear. The paper tries to show examples of both good practices and popularly committed mistakes, reminding some of well known researches as well as writers own experience.