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dc.contributor.authorSzewczyk, Rafał
dc.contributor.authorSoboń, Adrian
dc.contributor.authorRóżalska, Sylwia
dc.contributor.authorDzitko, Katarzyna
dc.contributor.authorWaidelich, Dietmar
dc.contributor.authorDługoński, Jerzy
dc.date.accessioned2015-06-15T09:23:24Z
dc.date.available2015-06-15T09:23:24Z
dc.date.issued2014-04-30
dc.identifier.issn1879-0208
dc.identifier.urihttp://hdl.handle.net/11089/9728
dc.description.abstract4-n-nonylphenol (4-n-NP) is an endocrine disrupting compound (EDC); pollutants that cause serious disturbances in the environment. This study shows the degradation pathway and initial proteome analysis in cultures of a fungus that actively degrades 4-n-NP, Metarhizium robertsii. The research revealed the presence of 14 4-n-NP metabolites formed as a result of the oxidation of the alkyl chain and benzene ring, which leads to the complete decomposition of the compound. Based on the trend and quantitative analysis of the formation of 4-n-NP derivatives, the best conditions for proteome analysis were established. The data collected allowed the formulation of an explanation of the microorganism's strategy towards the removal of 4-n-NP. The main groups of proteins engaged in the removal of the xenobiotic are: oxidation-reduction systems related to nitroreductase-like proteins, ROS defense systems (peroxiredoxin and superoxide dismutase), the TCA cycle and energy-related systems. Principal components analysis was applied to unidentified proteins, resulting in the formulation of three subgroups and initial classification of these proteins.pl_PL
dc.language.isoenpl_PL
dc.publisherElsevierpl_PL
dc.relation.ispartofseriesInternational Biodeterioration & Biodegradation;Volume 93, September 2014
dc.rightsUznanie autorstwa-Użycie niekomercyjne-Bez utworów zależnych 3.0 Polska*
dc.rightsUznanie autorstwa-Użycie niekomercyjne-Bez utworów zależnych 3.0 Polska*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/pl/*
dc.subjectMetarhizium robertsiipl_PL
dc.subjectfungipl_PL
dc.subject4-Nonylphenolpl_PL
dc.subjectBiodegradationpl_PL
dc.subjectProteomicspl_PL
dc.subjectMass spectrometrypl_PL
dc.subjectlc-ms/mspl_PL
dc.titleIntracellular proteome expression during 4-n-nonylphenol biodegradation by the filamentous fungus Metarhizium robertsiipl_PL
dc.typeArticlepl_PL
dc.page.number44-53pl_PL
dc.contributor.authorAffiliationFaculty of Biology and Environmental Protection, University of Łodz,pl_PL
dc.contributor.authorAffiliationAB SCIEX Germany GmbHpl_PL
dc.identifier.doi10.1016/j.ibiod.2014.04.026


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Uznanie autorstwa-Użycie niekomercyjne-Bez utworów zależnych 3.0 Polska
Except where otherwise noted, this item's license is described as Uznanie autorstwa-Użycie niekomercyjne-Bez utworów zależnych 3.0 Polska