http://hdl.handle.net/11089/40424 Dane badawcze zebrane w ramach projektów realizowanych na Wydziale Chemii | Research data collected as part of projects carried out at the Faculty of Chemistry 2026-04-03T19:01:41Z http://hdl.handle.net/11089/57734 Dataset for publication_Molecules 2025(30)4651_funded by National Science Center, Poland 2021/41/N/ST4/01425 Koszelska, Kamila; Świderski, Michał; Seroka, Jagoda; Guziejewski, Dariusz; Krzymiński, Paweł; Miniak-Górecka, Alicja; Ullah, Nabi; Smarzewska, Sylwia The study focused on evaluating the effect of electrode surface preparation on electrochemical measurements. In particular, the influence of different polishing protocols applied to carbon electrodes was investigated with respect to the electroactive surface area and the repeatability of the electrochemical response. The mechanical cleaning procedure of the solid disc electrode was systematically examined by testing various polishing motions and numbers of repetitions. The results demonstrated that the polishing method significantly affects both the electroactive surface area and measurement repeatability. The highest surface area and best repeatability were achieved using an “8-shaped” polishing motion. These findings confirm that electrode surface preparation plays a critical role in obtaining reliable and reproducible electroanalytical data. Dane badawcze powiązane z publikacją: Publikacja1. Świderski, M.; Seroka, J.; Guziejewski, D.; Krzymiński, P.; Miniak-Górecka, A.; Koszelska, K.; Ullah, N.; Smarzewska, S. Influence of Electrode Polishing Protocols, Potentiostat Models, and LOD Calculation Methods on the Electroanalytical Performance of SWV Measurements at Glassy Carbon Electrodes. Molecules 2025, 30, 4651. https://doi.org/10.3390/molecules30234651 In the file, measurement data obtained during voltammetric studies are provided. They present analyses carried out using different potentiostats, as well as various electrode surface renewal (cleaning/polishing) methods. 2025-01-01T00:00:00Z http://hdl.handle.net/11089/57733 Dataset for publication_Eng. Proc. 2023(48)65_funded by the National Science Center, Cracow, Poland (Grant no. 2021/41/N/ST4/01425) Machura, Gabriela; Seroka, Jagoda; Smarzewska, Sylwia; Koszelska, Kamila This study focused on the optimization of adrenaline electrografting onto a glassy carbon electrode using cyclic voltammetry in an acidic solution. A stable layer was obtained after multiple potential scans and characterized by square wave voltammetry. The results confirmed the successful formation of a stable adrenaline film on the electrode surface. Furthermore, the immobilized layer exhibited sensitivity to selected metal cations, as evidenced by a decrease in the adrenaline signal after exposure, indicating its potential application in indirect cation detection. The file contains measurement data obtained during voltammetric studies. It presents data collected during the deposition of adrenaline on the electrode surface and the subsequent optimization of this process. Additionally, it includes data aimed at verifying the sensitivity of the immobilized layer to the presence of Mg²⁺ and Ca²⁺ ions. 2023-01-01T00:00:00Z http://hdl.handle.net/11089/57576 Dataset for OPUS27 2024/53/B/ST5/00040 Kowalski, Konrad Kowalski, Konrad Dane dotyczą badania aktywności przeciwnowotworowej ferrocenylowej, biferrocenylowej pochodnej oraz cisPt wobec komórek nowotworowych raka płuca H1650, H1395, H2228 i A549 oraz cyklu komórkowego. Opisują też procedury służące do badań nad karbonylacją białek, ferroptozą i utlenianiem lipidów. Dataset powiązany z publikacją: Angelo Meoli, Chiara Riganti, Costanzo Costamagna, Przemysław Biegański, Joanna Kopecka, Konrad Kowalski, Two are better than one: A case study of the biferrocenyl-thymidine “click” conjugate biFcT as novel ferroptosis-inducing agent in lung cancer cells, Bioorganic Chemistry, Volume 163, 2025, 108690, ISSN 0045-2068, https://doi.org/10.1016/j.bioorg.2025.108690. 2025-03-23T00:00:00Z http://hdl.handle.net/11089/55089 Dataset to project MINIATURA 5 funded by the National Science Centre, Poland (grant number 2021/05/X/NZ8/01047) Krawczyk, Barbara; Zięba, Natalia; Kaźmierczak, Andrzej; Czarny-Krzymińska, Karolina; Szczukocki, Dominik Drug residues in the aquatic environment are a growing concern. The active ingredients of pharmaceuticals, such as antibiotics, hormonal agents or painkillers, can have negative effects on aquatic ecosystems and the organisms living in them. The research conducted was aimed at assessing the ecotoxicological risks associated with the use of bisoprolol and ketoprofen. The implementation of the above-mentioned studies was based on toxicological tests to determine the effect of selected drugs on the growth of Chlorella vulgaris and Desmodesmus armatus. The results that were obtained are alarming, as they show that the tested drugs have a negative impact on the tested species. Among other things, they cause inhibition of the growth of these organisms and a reduction in chlorophyll a content compared to control cultures. Ketoprofen proved to be particularly harmful. The tested pharmaceuticals induced oxidative stress in the mentioned microorganisms, as indicated by changes in the activity of antioxidant enzymes (catalase, peroxidase, superoxide dismutase, malondialdehyde). Profile area analyses showed that bisoprolol and ketoprofen treated C. vulgaris cells were approximately 4 and 2 times greater compared to control ones. Our experimental findings highlight the ecotoxicological threats for aquatic primary producers from bisoprolol and ketoprofen and provide insight into the characteristics of their death. Table 1a. The amount of chlorophyll “a”, biomass and the percentage of inhibition of Chlorella vulgaris and Desmodesmus armatus colonies exposed to bisoprolol Table 1b. Absorbance values obtained during enzyme determination in Chlorella vulgaris and Desmodesmus armatus colonies exposed to bisoprolol Table 1c. Cell profile area [μm2] (minimum (Min), maximum (Max) and median (Me)) of Chlorella vulgaris and Desmodesmus armatus exposed to bisoprolol Table 2a. The amount of chlorophyll “a”, biomass and the percentage of inhibition of Chlorella vulgaris and Desmodesmus armatus colonies exposed to ketoprofen Table 2b. Absorbance values obtained during enzyme determination in Chlorella vulgaris and Desmodesmus armatus colonies exposed to ketoprofen Table 2c. Cell profile area [μm2] (minimum (Min), maximum (Max) and median (Me)) of Chlorella vulgaris and Desmodesmus armatus exposed to ketoprofen 2022-01-01T00:00:00Z