http://hdl.handle.net/11089/30986 Fri, 03 Apr 2026 19:48:44 GMT 2026-04-03T19:48:44Z http://hdl.handle.net/11089/30991 Virological aspects of non-human primates or swine-to human xenotransplantation Mazurkiewicz, Natalia; Nowak, Agnieszka; Hryhorowicz, Magdalena; Zeyland, Joanna; Lipiński, Daniel; Słomski, Ryszard There are a number of human diseases, which can lead to organ failure. The consequence is often the need for a transplant. The number of performed operations is very low due to the shortage of organs for transplantation. As a consequence, the number of people waiting for transplant is still growing. The solution to this situation may be xenotransplantation. Xenotransplantation word comes from the Greek xenos meaning stranger, the other. It is defined as any procedure that involves the transplantation, implantation or infusion of tissues or zoonotic organs into a human recipient, but also human body fluids, cells, tissues, organs (or fragments) that have ex vivo contact with zoonotic cells, tissues or organs. One of the obstacles of the xenograft transplantation is the risk of animal pathogens transmission to the humans. Viruses that pose risk in the non-human primates-to-human xenotransplantation includes: the human immunodeficiency virus - HIV and the Marburg virus described in this paper. In addition viruses, which is a problem in pig-to-human xenotransplantation have also been described, including: porcine endogenous retrovirus - PERV, porcine cytomegalovirus - PCMV, porcine lymphotropic herpesvirus - PLHV and hepatitis E virus - E - HEV. This review of literature is the latest knowledge of the microbiological safety of xenotransplantation. Fri, 01 Feb 2019 00:00:00 GMT http://hdl.handle.net/11089/30991 2019-02-01T00:00:00Z http://hdl.handle.net/11089/30990 The spread of alien species along the touristic routes of the Słowiński National Park Krzyżanowska, Anastazja; Tomczyk, Przemysław Piotr; Pruszkowska-Przybylska, Paulina; Zielińska, Katarzyna Maria Touristic routes have a great meaning for the spread of alien species through the protected areas like national parks. The aim of the study was to assess the spread of the chosen species along the different kinds of touristic routes of the Słowiński National Park and asphalt roads lying in the direct vicinity of the Park, in its protective zone. The presence of 108 localities of eight alien species were recorded (Padus serotina, Quercus rubra, Acer negundo, Robinia pseudoacacia from woody species and Conyza canadensis, Impatiens parviflora, Juncus tenuis and Oxalis fontana from herbaceous plants). The localities of the woody plants were found in areas where they were formerly deliberately planted or near routes leading to such areas. All of the analysed woody plants can be the source of ecological threat and should be actively removed. Interestingly, regarding herbaceous plants, the species which according to literature are not a threat to untransformed habitats – Juncus tenuis and Oxalis fontana – were noted quite commonly. Their populations should be monitored. The populations of Impatiens parviflora, classified to the IV class of invasiveness and Conyza canadensis, which can invade sand dunes, should be destroyed as soon as possible till they occupy small areas. Fri, 01 Feb 2019 00:00:00 GMT http://hdl.handle.net/11089/30990 2019-02-01T00:00:00Z http://hdl.handle.net/11089/30989 The use of in vitro assays for the assessment of cytotoxicity on the example of MTT test Twarużek, Magdalena; Zastempowska, Ewa; Soszczyńska, Ewelina; Ałtyn, Iwona In recent years, biological tests have been developed based on cell cultures and successfully used to the hygienic assess of a variety of samples. In vitro assays become the complement of conventional chemical methods. They do not narrow the results only to the quantitative and qualitative information on toxic substances, but also increase knowledge on the direct impact on the organism. They are also an alternative for animal testing, which are currently given up for ethical reasons. At present, the market is steadily increasing in the number of tests and bio-assay techniques. Based on our own studies we conclude that the MTT test is perfect as a diagnostic method for evaluating the cytotoxicity of materials of different composition such as mycotoxins, pesticides, bacterial cultures, moulds isolates, food, feed, as well as a vast spectrum of other environmental samples. Fri, 01 Feb 2019 00:00:00 GMT http://hdl.handle.net/11089/30989 2019-02-01T00:00:00Z http://hdl.handle.net/11089/30988 Biodegradation of 3,5-dinitrosalicylic acid by Phanerochaete chrysosporium Madaj, Rafał; Kalinowska, Halina; Sroczyński, Witold; Szeląg, Jakub; Sobiecka, Elżbieta Despite intensive efforts put on prevention of environment pollution by nitroaromatic compounds, these xenobiotics have not been eliminated from the biosphere. The physicochemical properties make nitroaromatics extremely recalcitrant to biodegradation. Therefore, microbial degraders of these pollutants are sought after. This paper reports preliminary results of the study on degradation of 3,5-dinitrosalicylic acid (DNS) by a basidiomycetous fungus Phanerochaete chrysosporium under stationary conditions in a culture medium containing 0.05–0.5% v/v of DNS. The results obtained suggest that the fungus degrades DNS through the reductive pathway. Fri, 01 Feb 2019 00:00:00 GMT http://hdl.handle.net/11089/30988 2019-02-01T00:00:00Z