http://hdl.handle.net/11089/54556 Thu, 09 Apr 2026 13:10:04 GMT 2026-04-09T13:10:04Z https://dspace.uni.lodz.pl:443/xmlui/bitstream/id/dd9cd3ef-218e-4d01-bc5a-8ad6c0ce7c27/ http://hdl.handle.net/11089/54556 http://hdl.handle.net/11089/54563 Variability of anti-Müllerian hormone and folliculotropic hormone levels in women of reproductive age in relation to normal or impaired ovarian function Jusiakowska-Piputa, Małgorzata; Kaczmarek, Maria The demographic crisis in Europe is growing due to an increasing proportion of couples with fertility disorders. The purpose of this study was to examine the variability of ovarian reserve markers with age in women with premature ovarian insufficiency (POI) and polycystic ovary syndrome (PCOS) in relative to women with normal ovarian function. Two hormones were analyzed: anti-Müllerian hormone (AMH) and folliculotropic hormone (FSH). This study demonstrates that AMH is a valuable indicator of alterations in reproductive capacity. FSH is a standard marker of the hypothalamic-pituitary-ovarian axis.We examined the reproductive status of 390 women aged 23–46 years in three groups. Ovarian dysfunction was determined by a medical diagnosis. The study includes women with PCOS (n=154), POI (n=40), and control group (n=196) with normal ovarian function (NOF). Blood samples were collected to measure AMH and FSH. We used multivariate logistic regression analysis to demonstrate the relationship between hormone levels and age in different age groups. ANOVA was used to analyze factors related to AMH and FSH concentrations. The results confirmed that women with POI had significantly lower AMH concentrations and higher FSH concentrations than women with normal ovarian function only in the group of women aged 36–46 years. There were no statistically significant differences in FSH levels in women with POI and NOF in the 23–30 and 31–35 age groups. AMH levels were higher in the PCOS group than in women with NOF in all age groups. FSH marker did not differ compared to the control group in women aged 23–30 and 36–46. The predictive value of AMH in the diagnosis of PCOS is significantly higher than the commonly used FSH. The results may contribute to earlier assessment of biological status to support reproductive chances in women with POI and PCOS. Thu, 23 Jan 2025 00:00:00 GMT http://hdl.handle.net/11089/54563 2025-01-23T00:00:00Z http://hdl.handle.net/11089/54564 Anatomical alterations: biparietal thinning in antiquity. Review of published cases and a new case Rossetti, Nicol; Fusco, Roberta; Vanni, Arianna; Garanzini, Francesca; Mazzucchi, Alessandra; Licata, Marta Cranial anatomical variations, such as biparietal thinning, offer critical insights into the health and living conditions of ancient populations. Despite the presence of extensive archaeological records, biparietal thinning remains a relatively rare and understudied condition. This review aims to synthesize existing bioarchaeological literature on biparietal thinning, addressing its historical prevalence, geographical distribution, and potential etiologies.This study integrates data from previous bioarchaeological research supplemented with a new case from skeletal remains excavated at the hypogeal cemetery of Santa Maria Maggiore in Vercelli, Northern Italy. The analysis included macroscopic examination, radiological imaging, and comparative analysis with clinical and paleopathological cases to identify and assess the characteristic features of biparietal thinning.Our analysis of the skeletal remains of an old adult female individual revealed clear indicators of biparietal thinning. Notably, the thinning was bilateral, with the absence of diploe in the affected areas while maintaining the inner and outer tables of the cranial vault. These findings align with documented cases in the literature and contribute new data to the limited corpus of biparietal thinning cases.This study underscores the importance of integrating paleopathological findings with modern medical knowledge to enhance the understanding of ancient diseases. The case from Vercelli provides an opportunity to explore the multifactorial origins of biparietal thinning and highlights the necessity of a multidisciplinary approach, combining archaeological, anthropological, and medical perspectives. By presenting this new case, we aim to stimulate further research into biparietal thinning and similar cranial pathologies, enriching the broader narrative of human health evolution. Wed, 29 Jan 2025 00:00:00 GMT http://hdl.handle.net/11089/54564 2025-01-29T00:00:00Z http://hdl.handle.net/11089/54561 How do age and sex influence pain threshold and tolerance among Santal tribal people living in West Bengal, India? Santra, Arpita; Roy, Subrata Kumar; Goswami, Monali; Chatterjee, Diptendu The perception of pain, encompassing pain threshold and tolerance levels, is a complex phenomenon influenced by biological, psychological, and sociocultural factors. Notably, age and sex have consistently emerged as pivotal determinants in modulating pain perception. The study aimed to examine age and sex differences in pain threshold and tolerance levels. Furthermore, it delved into exploring whether age-related differences in pain threshold and tolerance levels vary between males and females. This study incorporated 484 healthy Santal tribal individuals aged 18–88 years (male 203 and female 281) living in Howrah and Purba Bardhaman Districts of West Bengal State, India, who reported no chronic or significant pain at the time of data collection. Pain threshold and tolerance levels were assessed using a digital algometer. Results of two-way ANOVA revealed significant main effects of age and sex on every pain threshold and tolerance level assessed in this study, indicating that older individuals had lower pain threshold and tolerance levels than younger ones. Males demonstrated greater levels of pain threshold and tolerance relative to females. Age and sex showed a significant interaction effect on pain tolerance levels, but not on pain threshold levels demonstrating the age-associated declining trend in pain threshold levels was consistent for either sex; however, such a tendency in pain tolerance levels was more pronounced in men. These findings highlight the importance of considering age and sex factors when assessing pain perception. Fri, 31 Jan 2025 00:00:00 GMT http://hdl.handle.net/11089/54561 2025-01-31T00:00:00Z http://hdl.handle.net/11089/54560 Changes in body composition (muscle mass and adipose tissue) among adolescents aged 11–15 from Kraków during the COVID-19 pandemic Artymiak, Paulina; Żegleń, Magdalena; Kryst, Łukasz Study aim: To assess changes in body composition, specifically focusing on muscle mass and adipose tissue, among adolescents aged 11–15 in Kraków during the COVID-19 pandemic.Materials and Methods: Cross-sectional studies were conducted in four selected districts of the city of Kraków in the years 2020 and 2022 (before and after the COVID-19 pandemic). The study group included adolescents aged 11–15 years. The percentage of body fat (%BF) was measured using the bioimpedance method. Additionally, measurements of height, arm circumference, and skinfold thickness of triceps were taken using a skinfold calliper. The collected data were used to calculate the Corrected Arm Muscle Area (CAMA). The normality of the distribution of each feature was assessed using the Shapiro-Wilk test. Statistical analysis was performed to compare differences between groups using two-way ANOVA with Tukey’s HSD post-hoc test or the Kruskal-Wallis test.Results: Among girls, a decrease in muscle mass was observed in most age categories. The opposite trend was observed among boys, as an increase in muscle mass was observed in most of the age groups. Girls were characterized by a decrease in the %BF in all cohorts, while in boys, an increase in the %BF was observed among 11,13 and 15-year-olds. In most age groups, there was an increase in the average muscle mass and increase in the %BF depending on BMI (Body Mass Index) categories in both sexes.Conclusions: This study found no notable variances in muscle mass and %BF within the examined group amid the COVID-19 pandemic. While certain outcomes indicated regression, possibly linked to reduced physical activity or prolonged sedentary periods, not all research findings exhibited decline. This could be attributed to online physical activity or enhanced dietary habits. Tue, 21 Jan 2025 00:00:00 GMT http://hdl.handle.net/11089/54560 2025-01-21T00:00:00Z