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Enantiodivergent Aldol Condensation in the Presence of Aziridine/Acid/Water Systems

dc.contributor.authorPieczonka, Adam
dc.contributor.authorRachwalski, Michał
dc.contributor.authorLeśniak, Stanisław
dc.contributor.authorMarciniak, Lena
dc.date.accessioned2021-10-22T08:13:06Z
dc.date.available2021-10-22T08:13:06Z
dc.date.issued2020
dc.identifier.citationPieczonka, A.M.; Marciniak, L.; Rachwalski, M.; Leśniak, S. Enantiodivergent Aldol Condensation in the Presence of Aziridine/Acid/Water Systems. Symmetry 2020, 12, 930. https://doi.org/10.3390/sym12060930pl_PL
dc.identifier.issn2073-8994
dc.identifier.urihttp://hdl.handle.net/11089/39512
dc.description.abstractA series of novel chiral imines was synthesized from corresponding aldehydes and 1-(2-aminoalkyl)aziridines with good chemical yields. Such imines were tested as catalysts in the direct asymmetric aldol reaction between aromatic aldehydes and acetone/cyclohexanone in the presence of catalytic amounts of water and an acidic additive. The corresponding aldol products were formed in excellent yields and with very high enantioselectivities (98% and 99% ee, respectively).pl_PL
dc.description.sponsorshipThis research was funded by the National Science Centre (NCN), grant number 2013/11/D/ST5/02911, which was awarded to A.M.P.pl_PL
dc.language.isoenpl_PL
dc.publisherMDPIpl_PL
dc.relation.ispartofseriesSymmetry;12
dc.rightsUznanie autorstwa 4.0 Międzynarodowe*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectasymmetric synthesispl_PL
dc.subjectenantiodivergent aldol condensationpl_PL
dc.subjectdiastereodivergent processpl_PL
dc.subjectaziridinespl_PL
dc.subjectchiral iminespl_PL
dc.subjectenantioselectivitypl_PL
dc.titleEnantiodivergent Aldol Condensation in the Presence of Aziridine/Acid/Water Systemspl_PL
dc.typeArticlepl_PL
dc.page.number13pl_PL
dc.contributor.authorAffiliationDepartment of Organic and Applied Chemistry, University of Lodz, Tamka 12, 91-403 Lodz, Polandpl_PL
dc.contributor.authorAffiliationDepartment of Organic and Applied Chemistry, University of Lodz, Tamka 12, 91-403 Lodz, Polandpl_PL
dc.contributor.authorAffiliationDepartment of Organic and Applied Chemistry, University of Lodz, Tamka 12, 91-403 Lodz, Polandpl_PL
dc.contributor.authorAffiliationThe Bio-Med-Chem Doctoral School of the University of Lodz and Lodz Institutes of the Polish Academy of Sciences, University of Lodz, 91-403 Lodz, Polandpl_PL
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dc.identifier.doi10.3390/sym12060930
dc.relation.volume930pl_PL
dc.disciplinenauki chemicznepl_PL


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Uznanie autorstwa 4.0 Międzynarodowe
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