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Diet as a Source of Acrolein: Molecular Basis of Aldehyde Biological Activity in Diabetes and Digestive System Diseases

dc.contributor.authorHikisz, Pawel
dc.contributor.authorJacenik, Damian
dc.date.accessioned2023-05-10T14:17:10Z
dc.date.available2023-05-10T14:17:10Z
dc.date.issued2023
dc.identifier.citationHikisz Paweł, Jacenik Damian: Diet as a Source of Acrolein: Molecular Basis of Aldehyde Biological Activity in Diabetes and Digestive System Diseases, International Journal of Molecular Sciences, Multidisciplinary Digital Publishing Institute (MDPI), vol. 24, nr 7, 2023, Numer artykułu: 6579, s. 1-23, DOI:10.3390/ijms24076579pl_PL
dc.identifier.issn1422-0067
dc.identifier.urihttp://hdl.handle.net/11089/47042
dc.description.abstractAcrolein, a highly reactive α,β-unsaturated aldehyde, is a compound involved in the pathogenesis of many diseases, including neurodegenerative diseases, cardiovascular and respiratory diseases, diabetes mellitus, and the development of cancers of various origins. In addition to environmental pollution (e.g., from car exhaust fumes) and tobacco smoke, a serious source of acrolein is our daily diet and improper thermal processing of animal and vegetable fats, carbohydrates, and amino acids. Dietary intake is one of the main routes of human exposure to acrolein, which is a major public health concern. This review focuses on the molecular mechanisms of acrolein activity in the context of its involvement in the pathogenesis of diseases related to the digestive system, including diabetes, alcoholic liver disease, and intestinal cancer.pl_PL
dc.language.isoenpl_PL
dc.publisherMDPIpl_PL
dc.relation.ispartofseriesInternational Journal of Molecular Sciences;24(7), 6579
dc.rightsUznanie autorstwa 4.0 Międzynarodowe*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectacroleinpl_PL
dc.subjectdiabetespl_PL
dc.subjectdietpl_PL
dc.subjectdiabetic retinopathypl_PL
dc.subjectdiabetic nephropathypl_PL
dc.subjectalcoholic liver diseasepl_PL
dc.subjectcolorectal cancerpl_PL
dc.subjectoxidative stresspl_PL
dc.subjectDNA adductspl_PL
dc.subjectα,β-unsaturated aldehydespl_PL
dc.titleDiet as a Source of Acrolein: Molecular Basis of Aldehyde Biological Activity in Diabetes and Digestive System Diseasespl_PL
dc.typeArticlepl_PL
dc.page.number1-23pl_PL
dc.contributor.authorAffiliationDepartment of Oncobiology and Epigenetics, Faculty of Biology and Environmental Protection, University of Lodz, ul. Pomorska 141/143, 90-236 Lodz, Polandpl_PL
dc.contributor.authorAffiliationDepartment of Cytobiochemistry, Faculty of Biology and Environmental Protection, University of Lodz, ul. Pomorska 141/143, 90-236 Lodz, Polandpl_PL
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dc.contributor.authorEmailpawel.hikisz@biol.uni.lodz.plpl_PL
dc.identifier.doi10.3390/ijms24076579
dc.disciplinenauki biologicznepl_PL


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