Krzepnięcie krwi i fibrynoliza w zatruciu etanolem i acetaldehydem
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Data
1988Autor
Skrzydlewski, Zdzisław
Worowski, Krzysztof
Skrzydlewska, Elżbieta
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Rats intoxicated with ethanol and acetaldehyde during 2 months showed increase
of the thromboplastic activity in the kidney homogenate and decrease
of this activity in the lung homogenate. Besides the intoxication with acetaldehyde
increased activity of plasminogen in the homogenate of these organs.
Antiplasmin activity decreased in the kidney and lung homogenates after one
months and in the stomach homogenate after two months of intoxication with
ethanol and acetaldehyde. The time of recalcination and the prothrombin time
were slightly shorter in the plasma of rats intoxicated with ethanol and acetaldehyde
and the fibrinogen level was increased. The time of the euglobulin
fibrinolysis is slightly prolonged after the two months intoxication. The plasminogen
level was simultaneously slightly increased. The antiplasmin activity
was slightly decreased after one month of the intoxication with ethanol and
acetaldehyde but in the second month of the intoxication the activity of this
inhibitor was slightly -increased.